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Trial NCT06619587

A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

Phase
Phase 1
Sponsor
Genentech, Inc.
Conditions
Solid Tumor
Ages
18+ years
View on ClinicalTrials.gov ↗

Eligibility criteria

Highlighted: restrictions our model extracted, each a verbatim quote (pink = excludes outright, blue = only under conditions).

Inclusion Criteria: * Histologically documented advanced or metastatic solid tumor with KRAS G12D mutation * Agreement to adhere to the contraception requirements described in the protocol for participants of childbearing potential and participants who produce sperm Exclusion criteria: * Malabsorption or other condition that would interfere with enteral absorption * Active brain metastasesBrain metastases * Clinically significant cardiovascular dysfunction or liver diseaseCardiac · Hepatic

Restrictions found (3)

Recruiting in Massachusetts

  • Dana Farber Cancer Institute · Boston, Suffolk County