The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma

Inclusion Criteria: 1. Age ≥18 years and ≤90 yearsAge 2. Tumor recurrence according to the RANO criteria of a previously diagnosed glioblastoma based on the WHO 2021 classification for glioma 3. Tumors situated in or near eloquent areas; motor cortex, sensory cortex, subcortical pyramidal tract, speech areas or visual areas as indicated on MRI (Sawaya Grading II and II)19 4. The tumor is suitable for resection (according to neurosurgeon) 5. Written informed consent Exclusion Criteria: 1. Tumors of the cerebellum, brainstem, or midline 2. Multifocal contrast-enhancing lesions 3. Medical reasons precluding MRI (e.g., pacemaker) 4. Inability to give written informed consent 5. Secondary high-grade glioma due to malignant transformation from low-grade glioma 6. Clinical data unavailable for the newly diagnosed setting