Trial NCT03295981
Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone
- Phase
- Phase 3
- Sponsor
- St. Louis University
- Conditions
- Giant Cell Tumor of Bone
- Ages
- 18+ years
Eligibility criteria
Highlighted: restrictions our model extracted, each a verbatim quote (pink = excludes outright, blue = only under conditions).
Inclusion Criteria:
* Primary benign GCT of bone
* Lesion located in an extremity
* Lesion amenable to reconstruction (intralesional curettage) defined as having at least one intact column of bone after removal
* No previous systemic bisphosphonate or denosumab therapy
Exclusion Criteria:
* Recurrent GCT of bone
* Non-extremity location
* Lesion too extensive for intralesional treatment, either due to bone loss, joint invasion, or large soft tissue component
* Children and pregnancyPregnancy
* Previous systemic bisphosphonate or denosumab therapy
Restrictions found (1)
- PregnancyOutrightexclusionShow in the text
Recruiting in Massachusetts
- Massachusetts General Hospital · Boston, Suffolk County
- Boston Children's Hospital · Boston, Suffolk County
- Beth Israel Deaconess Medical Center · Boston, Suffolk County